No. The Fellowes Air Purifier will not hurt the Ozone layer. Appliances hurting the Ozone layer are cooling appliances such as air conditioners and refrigerators which release Freon gas into the air. Fellowes Air Purifiers do not release any Freon gas and therefore, do not hurt the Ozone layer.
In addition, the Environmental Protection Agency has National Ambient Air Quality Standards for pollutants considered harmful to public health and the environment. These standards provide public health protection, including protecting the health of "sensitive" populations such as asthmatics, children and the elderly.